EPITALON peptide or Epithalon, AGAG, AE-0 peptide, AEDG is a synthetic epiphysis tetrapeptide–telomerase activator and potential anti-aging drug developed at the St. Petersburg Institute of Bioregulation and Gerontology in the research group of Professor V. Khavinson.
The peptide was made based on the amino acid analysis of epithalamin (a concentrate of the pineal gland – a neuroendocrine system bioregulator, which is the sum of peptides) and has the following sequence of amino-acids: Ala-Glu-Asp-Gly.
The biological activity of epithalon, according to the data on human fibroblast cell cultures in vitro, is based on the induction of telomere elongation by increasing telomerase activity in human somatic cells. 1
The elongation of telomeres by epitalon is sufficient to exceed the Hayflick limit (the limit of the number of somatic cell divisions in cell culture is 50 divisions due to telomere shortening of the DNA molecule with each cell division).
Athletes and bodybuilders use Epitalon
What is it used for? In the world of sports, as one of the bodybuilding peptides, cosmetology, and medicine, Epitalon is actively used for quick recovery of physical activity and energy balance loss after workouts.
In its structure, Epitalon is a chain of 4 amino acids, which is why in the world of sports it is known as AGAG. This short peptide has been known for more than 30 years already. The substance was found in the brain extracts of animals. Initially, it was tested on animals.
The research data proved that Epitalon has a regenerating and life-prolonging effect. It also has a positive effect on the hormonal levels and thyroid gland.
Epitalon helps to prevent the early ageing process of cells. Later Epitalon-based analogues of this peptide (Epitalamin, Endoluten, and Pineamin) were developed. However, Epitalon takes the lead position among them.
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What are the advantages of using it?
The main Epitalon benefits are:
- extended life expectancy; 2
- rejuvenating effect;
- sleep normalization
- additional strength;
- rapid regeneration of damaged cells;
- accelerated recovery after the training;
- averting dangerous diseases;
- skin improvements;
- increased endurance.
Dosages and cycling
According to the instructions, the peptide can be administered by different methods. It is worth considering that the oral method is considered the longest and most ineffective. The intramuscular method of administration of the drug is considered preferable in the world of sports. Injections of the active ingredient under the skin guarantee the rapid entry of the drug into the bloodstream.
The number of cycles depends on the desired result of the athlete and the individual characteristics of the body. It is recommended to consult a sports coach before injecting the peptide. This will help to prevent the occurrence of unwanted side effects and other troubles.
The effectiveness of Epitalon directly depends on weight, age, the dosage of the peptide, and time of injection.
The following cycle of the peptide is recommended for athletes:
- The optimal daily Epitalon dosage is 5-15 mcg per 1 kg of body weight.
- The duration of the cycle is 2 months, which is about 2 vials;
- After a two-month cycle, a break is recommended.
It is recommended before the first use of the peptide to carefully analyze its composition and the rules for the use and dilution of the drug. This will help to accurately dial in the dosage and prevent the development of an allergic reaction.
When used orally, the peptide is used at a dosage of 400-600 mcg/day (the dosage should be divided into 2-3 doses). In the form of a spray, Epitalon is sprayed at 1-30 mg/day (the dosage is divided into 3 uses).
An unlimited number of epitalon cycles can be. It is recommended that beginners take a 4-month break every 15 days. This will allow you to conclude the effectiveness of the drug and its further use.
Important! Chills that appear after the injection are an additional reason to consult with your sports coach.
Since the peptide is sold in powder form, it is necessary to know how to properly dilute the dry substance. To dilute Epitalon, add 1-2 ml of distilled water to the bottle. The liquid should be poured in a thin stream. No sudden movements are allowed after filling the vial. The drug is mixed with water through smooth movements. Many people think that it is not necessary to stir the peptide because it has excellent solubility.
Epitalon spray is a new generation drug based on short peptide technology. It restores the proper functioning of the epiphysis (pineal gland) and regulates the production of serotonin and melatonin.
The epiphysis is located in the very centre of the brain and plays a key role in all bodily systems. It produces about 40 types of bioactive compounds and affects overall physical health. It has an immune-stimulating effect.
The results of Epitalon use will be the improvement of sleep quality, vivacity, the general strengthening of protective functions of the body, and normalization of the immune system at the cellular level.
Due to its high efficiency and significance, Epitalon spray is the leader among peptide sprays in the world.
- Sleep disorders, insomnia
- Fatigue, stress;
- Impaired immunity;
- Disruption of the human biorhythm;
- Jet lag (sleep disturbances caused by long flights);
- hormonal disorders.
It is not recommended for children and adolescents. It is not recommended to exceed the dose without a doctor’s prescription.
Epitalon is not hormonal, so it has no toxic effect on the body. It has no side effects and does not cause complications or drug dependence. Due to its mild action, it does not cause complications for the liver and kidneys.
Where to buy online?
You can order original Epitalon 10mg from the SwissChems website.
- All their products are HPLC verified.
- Local USA delivery is 1-5 days on all products.
The seller has all the key peptides and SARM items for sale.
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Epitalon is a unique peptide that gives a quick burst of additional energy, strength, and stamina. The action of the drug helps to achieve excellent results in sports.
Read Epitalon peptide testimonials below or write your own review!
Mike Lilley is the author of many articles and reviews on our site. He is a fitness & bodybuilding blogger and co-founder of Boost Hormone. He writes product reviews based on the results of scientific research. From the great variety of information and products in this niche, he recommends only those that include science-based nutritional ingredients. Find Mike Lilley at SelfGrowth.
Submit your review
I have been using Epitalon for over 5 years now. The usual duration of my cycle is 45 days. Sometimes I add Timalin also for better results. I noticed that I could train without any fatigue. My strength keeps on coming back. My friends say that I look at least 5 years younger than my age. After the cycle, I take a six-month break.
Actually it's a great stack of peptides Mike - Timalin + Epitalon!
- V. Khavinson, E. Bondarev, A. Butyugov
– “Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells” – https://pubmed.ncbi.nlm.nih.gov/12937682/
Bull Exp Biol Med. 2003 Jun;135(6):590-2. doi: 10.1023/a:1025493705728.
- V K Khavinson, D M Izmaylov, L K Obukhova, V V Malinin
– “Effect of epitalon on the lifespan increase in Drosophila melanogaster” – https://pubmed.ncbi.nlm.nih.gov/11087911/ Mech Ageing Dev. 2000 Dec 1;120(1-3):141-9. doi: 10.1016/s0047-6374(00)00217-7.