Ligandrol (LGD 4033) – the most popular and one of the most effective SARMs for gaining lean body mass available on the market today.
It has properties comparable in strength to anabolic steroids. It is recommended for those involved in bodybuilding, fitness, and strength sports and stacks well with Ibutamoren.
Ligandrol is a very effective and quite safe SARM. It belongs to the selective androgen receptor modulators. While taking it, it speeds up recovery, accelerates anabolism, and activates the fat-burning process.
The main effects of Ligandrol
- Acceleration of muscle growth: many notice an increase in muscle mass
- Strengthening of bones and ligaments: found to raise anabolic activity in muscles and bones
- Increasing strength and endurance in sports
- Fat burning effect
- Accelerates the recovery of the body after high physical activity
- Increased levels of naturally produced testosterone
Strength and muscle mass increase?
First of all, Ligandrol LGD-4033 is recommended for use during the period of gaining lean muscle mass. The results of the product can be seen even during the first week of taking it. It is also recommended for athletes practicing power sports and crossfit since it contributes to a significant increase in strength and endurance. It can be used by both amateur and professional athletes.
The supplement provides good results both when taken solo and in stacks with other SARMs, such as Ibutamoren. It is important to notice that after taking the cycle, you may need PCT (depends on individual tests before and after the cycle).
How does Ligandrol work?
Its mechanism of action is due to the selective activation of testosterone receptors in muscle and bone tissues without affecting the receptors in the pituitary gland, prostate, sex, and sebaceous glands, hair follicles.
Testosterone receptor activation in muscles results in enhanced synthesis of muscle protein and faster replenishment of muscle glycogen reserves. This results in increased efficiency of oxidative reactions and potentiation of fat utilization.
Stimulation of androgen receptors in bone prevents calcium resorption and contributes to increased bone strength. The increase in strength also happens in joints, tendons, and ligaments. Therefore, the use of Ligandrol is recommended for the prevention of sports injuries.
Ligandrol does not affect the receptors contributing to the synthesis of hormones, ensuring stable levels of testosterone, follicle-stimulating, or luteinizing hormone. The possibility of increasing estrogen levels and the development of gynecomastia is excluded since the aromatase enzyme does not act on Ligandrol.
Clinical trials
In the beginning, Ligandrol was used in medical practice to treat muscular dystrophy. And then it found great popularity in the world of sports as an effective and safe supplement. The Journals of Gerontology, Series A, Biological Sciences and Medical Sciences published about clinical trials in March 2012 examining the effects of LGD-4033 on the human body. 1
A group of men between the ages of 21 and 50 was given 5 to 25 mg daily. As a result, positive results were obtained: the muscle mass increased, while their blood test and hormones level remained normal. This trial has once again scientifically confirmed the high efficacy and safety of Ligandrol.
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- Visit Ligan 4033 page to get the Ligandrol supplement formula
Ligandrol results
Taking capsules provides quality weight gain that is not associated with fluid retention in the body. This guarantees a sustained effect after you stop taking it. Muscle gain during the 90 days’ cycle is from 8 to 12 kg, the after cycle loss is about 0.5 to 1 kg. In addition to gaining lean muscle mass, the drug promotes fat burning and strength gains.
Contraindications
- Under 18 years of age;
- Pregnancy and lactation;
- Individual intolerance to the product components.
Ligandrol cycle dosage
The daily doses depend on the bodyweight of the person. Up to 110 kg – you should take 1 capsule per day, 110 kg and above – 2 capsules. The recommended cycle length is 8-12 weeks. The standard dosage of the product for increasing muscle mass is 1 capsule per day for 8-12 weeks.
To achieve the greatest effect, stick to a diet rich in protein and healthy calories. More noticeable body recomposition (reduction of fat mass while maintaining total body weight) is achieved when stacking LGD-4033 with other SARMs. To improve lipolytic activity, 1 capsule every other day for 8 weeks is indicated.
Ligandrol and Ostarine stack
Among the most popular cycle stacks is usually the simultaneous taking of Ligandrol and Ostarine. While the former provides tremendous growth of muscle mass, the latter further stimulates hypertrophy and makes the musculature leaner and tougher. This bundle demonstrates the advantage, which is the reason for such great popularity.
Other Ligandrol stacks:
For muscle size and stiffness:
Lean muscle mass gain
- LGD-4033 + MK-677;
- LGD-4033 + YK-11.
PCT for Ligandrol
There are often when Ligandrol suppresses your testosterone production. If you feel sluggish and tired at the end of the cycle, the level of this hormone is probably approaching the lower limit.
I advise taking testosterone boosters throughout the cycle, as well as doing PCT with test boosters after the LGD-4033 cycle.
According to the experience of athletes, you don’t need to do PCT treatment at the maximum dosage of 5 mg for 8 weeks, but it’s still a very low dosage in my opinion. If you increase the dosage to 10 mg and stretch the cycle over 10 weeks, your testosterone level production starts to drop.
Ligandrol SARM side effects and risks
The development of hypersensitivity reactions is possible. Symptoms of overdose have not been established.
No effect on prostate-specific antigen has been found. The effects of Ligandrol (Ligandrol, LGD 4033) are similar to anabolic steroids in muscle gain and strength improvement. Its advantages include efficacy, which is 4 times higher than that of Ostarine (Ostarine MK-2866), absence of side effects, increase of strength and endurance, an increase of lean muscle mass without loss, burning of subcutaneous fat, good interaction with Ibutamoren.
Bad cholesterol
While there is limited research on the effects of ligandrol on cholesterol levels, some studies have suggested that it may increase levels of low-density lipoprotein (LDL) cholesterol, commonly known as “bad” cholesterol. It is important to note that the long-term effects of ligandrol on cholesterol levels still need to be fully understood, and more research is needed to determine its safety and efficacy.
Hair loss
Regarding hair loss, there is limited research on the potential effects of Ligandrol on hair health. Androgens, such as testosterone, have been linked to hair loss in some individuals. Since Ligandrol is a SARM that targets androgen receptors in the body, it may contribute to hair loss in some individuals. However, more research is needed to determine the specific effects of Ligandrol on hair health.
Where to buy it chaper?
You can order Ligandrol online from couple trusted brands! Here is our short list of the best SARM companies (you will find discount coupons from each vendor). Check the reviews to buy Ligandrol and other SARMs online for less.
Reviews of Ligandrol
Ligandrol reviews are mostly positive. Users report that taking the SARM and working out in the gym contributes to a noticeable burning of fat, the appearance of beautiful muscles. Laboratory tests after four weeks of taking the capsules confirmed the absence of abnormal testosterone levels and changes of hepatic parameters.
Mike Lilley is the author of many articles and reviews on our site. He is a fitness & bodybuilding blogger and co-founder of Boost Hormone. He writes product reviews based on the results of scientific research. From the great variety of information and products in this niche, he recommends only those that include science-based nutritional ingredients. Find Mike Lilley at SelfGrowth.
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References:
Shehzad Basaria, Lauren Collins, E Lichar Dillon, Katie Orwoll, Thomas W Storer, Renee Miciek, Jagadish Ulloor, Anqi Zhang, Richard Eder, Heather Zientek, Gilad Gordon, Syed Kazmi, Melinda Sheffield-Moore, Shalender Bhasin – “The safety, pharmacokinetics, and effects of LGD-4033, a novel nonsteroidal oral, selective androgen receptor modulator, in healthy young men” – https://pubmed.ncbi.nlm.nih.gov/22459616/
J Gerontol A Biol Sci Med Sci. 2013 Jan;68(1):87-95.
doi: 10.1093/gerona/gls078. Epub 2012 Mar 28.