Ostarine (MK-2866) belongs to the SARMs, which open a new page in the history of sports pharmacology. We are talking about selective androgen receptor modulators, unique chemical compounds capable of selectively activating testosterone receptors in muscle tissue.
The SARM will get you out of the quagmire of the training plateau, stimulate lean muscle mass gain, and accelerate fat burning. And all of this without the side effects of anabolics! Continue reading our Ostarine review to learn all about it.
What is Ostarine?
Ostarine does not bind to sex hormones or to globulin that binds sex hormones, but to receptors in tissues. Thus, muscle mass increases and workouts are easier to tolerate with this drug.
The following effects have been researched and confirmed:
- An increase in lean muscle mass; 1
- Strengthening of bone and cartilage tissue;
- Increase in metabolic rate;
- Boosting the effects of anabolic steroids and other SARMs
SARM is similar to Andarine but with a different chemical formula. The above suggests that Ostarine and Andarine work better together.
How does Ostarine work?
Its key feature is its selective action on receptors in muscles, tendons, adipose tissue, cartilage, and bones. By binding to testosterone receptors in the muscles, it blocks catabolism, turns on the anabolic engines and starts the synthesis of contractile proteins. The result is a rapid accumulation of muscle mass.
Activation of receptors in fat cells boosts fat burning. At the same time, Ostarine changes the vector of energy distribution: the calories from food go to the metabolically active muscle tissue and are not deposited in fat. Activation of androgen receptors in the bones leads to an increase in their mineralization (strength). A similar effect is achieved in tendons and joints.
Testosterone receptors in other organs – in the pituitary gland, hypothalamus, or sex glands – are not affected by Ostarine and therefore do not inhibit the production of their own hormones, do not lead to prostate problems, and do not provoke hair loss. Ostarine is not aromatized, does not lead to water accumulation in the muscles, and does not cause side effects associated with an increase in estradiol.
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Who will benefit from taking Ostarine?
Ostarine is used in bodybuilding and fitness: it accelerates muscle growth, makes it as easy as possible to lose weight, and is good for cutting.
Ostarine is also good for boxers, wrestlers, and cross-fitters who need to strengthen their joints and ligaments to avoid unfortunate injuries. Another area of application is in sports disciplines that require inhuman endurance. For example, cycling, swimming, and athletics.
Important: Ostarine is neither a steroid nor a peptide hormone. Both men and women can take Ostarine. Women in fitness bikini, for example, use it to improve tissue composition and prepare for competitions.
The main benefits are:
- It’s effective: fast weight loss and quality muscle mass gain without rolling back;
- It’s convenient: it is available in capsules and does not require injection;
- It can be used by men and women;
- It’s safe: does not inhibit testosterone synthesis.
Because of its anti-catabolic action, it has been successfully used in PCT to prevent muscle protein breakdown and reduce muscle loss after a cycle. Experienced bodybuilders take Ostarine when “building bridges” between steroid cycles.
Another use is injury prevention. Only beginners do not think about this aspect of strength training (as well as any other sport), while experienced athletes pay enough attention to preventive measures. Ostarine strengthens ligaments, tendons, and joints, thus reducing the risk of injury. If the injury has already happened, it will speed up the restoration and help you get back to the gym faster.
Here are the areas of application of Ostarine in sports:
- Mass gain;
- Cutting and losing weight;
- Bridges between cycles;
- Injury prevention;
- Recovery after injuries.
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Ostarine dosage and cycle instructions
Recommended dosage: 1-2 capsules for men. 1-2 times a day, 1 capsule once a day for women.
Note that the anabolic effect occurs after as low as 5 mg per day, while 12.5 mg/day is sufficient to strengthen bones, ligaments, and joints.
The recommended duration of the MK 2866 cycle is 30–60 days.
If we are talking about strength and speed sports, you should take the drug only after you have already reached a certain level in the sport. It is worth understanding that for adequate muscle growth, it is necessary to train according to a well-designed program, to stick to an adequate diet, and to get enough sleep. Still, SARMs are not a magic pill for turning a beginner into an athlete.
Proper dosages and the cycle length
The standard male solo dosage starts at 25 mg and can progress to 75 mg. A single dose of the drug is an adequate choice for a beginner.
Ostarine solo cycle has the following effects:
- Anabolic – boosts weight gain;
- Anti-catabolic – prevents protein breakdown;
- Lipolytic – accelerates fat burning;
- It increases endurance by 50%;
- It increases in strength;
- It increases bone density;
- Strengthening of ligaments and tendons.
Possible side effects
There can be a slight nervous excitement at the beginning of the MK 2866 cycle, sometimes a fever and sweating. You should monitor the levels of LH, FSH, and testosterone. The SARM tends to “drop” its own production of male sex hormone after the cycle, so PCT is needed. Take half the prescribed dose of clomiphene citrate.
It is strictly not recommended to take it in the case of liver and kidney diseases. Such athletes should be guided by ALT and AST values when choosing a drug for the cycle.
What to stack MK 2866 with?
The most popular Ostarine stack is 7 mg each of Ostarine and Andarine plus Ibutamoren in a personalized dosage. Such a cycle will both maintain or even increase muscle mass and burn fat at the same time.
Ostarine can also be stacked with prohormones like DMZ, Epistane, and Epitrenol. Such MK 2866 cycle are made for extreme weight gain. They can slightly increase prolactin levels, which is corrected by Cabergoline on tests. Ostarine can also be combined with prohormones such as DMZ, Epistan, and Epitrenol. Such courses are made for extreme weight gain. They can slightly increase prolactin levels, which is corrected by Cabergoline after the tests are done.
How to stack Ostarine to gain muscle mass?
- Ostarine + Andarine + Ibutamoren for 8-12 weeks.
- Ostarine + Ligandrol for 8-12 weeks.
- Ostarine + DMZ for 8 weeks.
- Ostarine + Epistan for 8 weeks.
Ostarine stacks for cutting?
- Ostarine + Ibutamoren + Laxogenin for 8-12 weeks.
- Ostarine + Cardarin + Andarine for 8-12 weeks.
- Ostarine + Keto DHEA for 8-12 weeks.
- Ostarine + 19-nor-andro + Superdrol for 8 weeks.
Where to buy Mk 2866 Cheaper?
You can order Ostarine online from a couple of trusted brands! Here is our short review of the best SARM companies (you will find discount coupons from each vendor). Check the list to buy Ostarine and other SARMs online for less.
Answers to some popular questions
How to boost the effects of the drug?
It is recommended to stack several SARMs rather than increasing the dosage of Ostarine or the duration of the cycle. In general, the golden rule of taking SARMs is to alternate and to stack them.
What is the maximum duration of the cycle?
12 weeks. Increasing the length of the cycle will not only give a better result, but increase the risk of side effects.
What would be the dosage not for athletes? If I want to maintain muscle tone and a low fat percentage.
The instructions for use of MK 2866 for medical purposes range from 3 to 7 mg.
Should I reduce the dosage of Ostarine in stacks with other SARMs?
Reduced doses should be adhered to if Andarine or Testolone are present in the stack. When taken together with anabolic steroids and prohormones, choose 7 to 12 mg of the drug each day.
How should women take Ostarine?
It is recommended that women start with 5 mg and gradually increase the dosage, but do not go above 20 mg.
How do I take Ostarine throughout the day?
For the sake of better digestibility, usually the working dose is divided into 2 parts. Capsules are taken on an empty stomach and before training, if there are no problems with the gastrointestinal tract. For those who do not tolerate pills, it is recommended to postpone the first and take it after breakfast.
Women should start the cycle on the first day of their new menstrual cycle. Men can start at any convenient time.
The length of the cycle is 6 to 12 weeks. Shorter periods are recommended for beginners.
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Mike Lilley is the author of many articles and reviews on our site. He is a fitness & bodybuilding blogger and co-founder of Boost Hormone. He writes product reviews based on the results of scientific research. From the great variety of information and products in this niche, he recommends only those that include science-based nutritional ingredients. Find Mike Lilley at SelfGrowth.
- Paul Jonathan Roch, Danny Henkies, Jan Christoph Carstens, Carsten Krischek, Wolfgang Lehmann, Marina Komrakova, and Stephan Sehmisch
– “Ostarine and Ligandrol Improve Muscle Tissue in an Ovariectomized Rat Model” – https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7528560/
Front Endocrinol (Lausanne). 2020; 11: 556581. Published online 2020 Sep 17. doi: 10.3389/fendo.2020.556581