- 1 How does it work?
- 2 Principles of working of MK-677
- 3 How to Stack MK-677 SARM for the best cycle results?
- 4 Research
- 5 MK-677 benefits and results:
- 6 Results you can get:
- 7 MK-677 dosage
- 8 What form of MK-677 SARM is better: capsules, liquid, or powder?
- 9 Side effects of MK-677
- 10 What’s the period of a cycle?
- 11 Best place to buy MK-677 online? Recommended SARMs Vendors
To the end of our MK-677 SARM review, you will know how the product works and it’s key benefits, which other SARMs you can stack Ibutamoren with for the best cycle results, which form of MK-677 is better – capsules, liquid or powder?
MK-677 SARM (Ibutamoren, Nutrobal) stimulates the production of growth hormone (somatotropin). 1 It also supports the level of growth hormone in plasma, so it is produced stably, without disruptions.
Ibutamoren also promotes the production of ghrelin, a peptide hormone that regulates food intake. Thus, balanced metabolism is maintained.
MK-677 allows the release of IGF-1 – a protein produced in the liver and muscles. 2 In this case, the drug does not affect the natural production of cortisol. The level of steroids in the body will not exceed the norm.
How does it work?
Ibutamoren is one of the best legal alternatives to the human growth hormone. It is very effective and has a stimulating effect on the metabolic process in the body.
It reliably strengthens the density of the bones while on a cycle. Ibutamoren is believed to have a positive effect on brain activity, and the central nervous system.
MK-677 effectively increases the secretion of growth hormone in people of all ages. It has advantages over the other ghrelin agonists because it is not a peptide, does not degrade in the gastrointestinal tract, and therefore remains active. An athlete can simply take 25 mg of Ibutamoren once a day, and it is much more convenient than injecting a peptide.
MK-677 binds to the ghrelin receptor by mimicking the effects of this peptide hormone. These anabolic and endocrine effects are expressed in increased appetite, increased muscle mass, increased bone mineral density, angiogenesis (creates new and strengthens existing blood vessels), heart protection, glucose modulation, and energy homeostasis.
Principles of working of MK-677
The main advantage is that the substance does not affect cortisol. That is why Ibutamoren is recommended for morning and evening use without fear of negative effects of GHRP. Fat deposits are burned by increasing lipolysis. 3 Active components of the product accelerate metabolism, so MK-677 is classified as a substance of growth hormones, not the peptides themselves. Tests have shown that a dosage of 25-30 milligrams is comparable in efficacy to take injectable HGH.
A distinctive feature of MK-677 is the stimulation of GH release over a long period, in contrast to other drugs. Ibutamoren affects HGH production for 8 hours, which can be safely attributed to the benefits of the substance.
How to Stack MK-677 SARM for the best cycle results?
MK-677 can be combined with various sports nutrition products to achieve maximum results during the training.
- Among bodybuilders, a combination of Ligadrol and Ibutamoren in a 1:1 ratio is very popular. The cycle duration does not exceed 2 months. Optimal dosage per day – 20 milligrams. This helps to quickly gain weight, lose fat, and increase strength.
- Some people prefer to use Ibutamoren together with Ostarine (MK-2866, Enobosarm). It’s a legal combination that helps to increase strength and weight. The maximum cycle period is eight weeks. Specialists note that the drug can be combined with almost any steroid.
Unlike most similar products, Ibutamoren is suitable for long-term use. It has an accumulative effect and stably influences hormones, contributing to the growth of their level. Read more about the best SARM stacks here.
Observations of the experimental group (65 men and women) showed that the drug significantly reduces the proportion of fat in the body and at the same time helps accelerate metabolism and muscle gain. No serious side effects were detected, which indicates that the drug is safe. 4
MK-677 SARM actively increases the level of growth hormone – in 6 weeks this figure reaches 60%.
Specialists already now assume that the drug can be taken by the elderly and children, as it is potentially harmless to the body.
MK-677 benefits and results:
- A big advantage of Ibutamoren is the fact that it does not affect cortisol levels,5that is, it does not contribute to the production of steroids, excess of which can seriously affect testosterone levels in the body.
- Ibutamoren is also not a peptide, i.e. there is no risk of exceeding the amino acid levels in the body.
- The drug is similar to the injections of growth hormone, but it is painless, and you can take the drug at any time and in any place.
- If you read Ibutamoren reviews on the Internet, the vast majority of users see the positive results of the drug – both in sports and in overall health.
Results you can get:
- On a short-term diet, a dose of MK-677 SARM 20 mg once a day contributed to a significant improvement in appetite, while the fat mass can be decreased and the muscle mass increased, up to 4 kg in 2 months.
- After 7 days of taking the dose, there will be an increase in the level of growth hormone as well as an improvement in general well-being.
- Acceleration of metabolism is observed after 2 weeks of use.
- MK-677 can improve results in the treatment of osteoporosis and other bone diseases – according to specialists’ observations, the density of bones increases significantly, which is important not only for professional athletes.
- Ibutamoren has several additional positive properties. It helps to improve sleep, increase energy levels, and overall well-being. In some people who have used the drug, immune system strengthening has been noted.
- Nutrobal can be used not only by professional athletes but also by those who need to stabilize and keep metabolic processes at an optimal level.
Here are some basic useful benefits of Ibutamoren:
- Fat loss;
- Muscle mass gain;
- Improving skin tone;
- Healing of injuries;
- Accelerated regeneration of bones, tendons, and ligaments.
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According to the research results, the optimal dosage of MK-677 is 10 to 25 mg. This dosing effect is similar to that of the growth hormone injected intramuscularly. In this case, many people prefer a painless method.
What form of MK-677 SARM is better: capsules, liquid, or powder?
This product is available in both powder and liquid form. There is also a capsule form which we believe is the most preferable, you can carefully divide the dosage and break it into several equal parts. The half-life of Ibutamoren is 24 hours. Most people take it before going to bed, as it is known to cause sleepiness.
Side effects of MK-677
Most people who have used the drug for some time noted only its positive effects. However, Ibutamoren may cause symptoms typical of elevated levels of growth hormone, in particular sluggishness. There is also a significant improvement in appetite associated with increased storage of glycogen in muscle tissue.
What’s the period of a cycle?
Use 1 capsule (25mg) 4 or 7 days, after that make a pause for 2-5 days.
Attention! Nutrobal is considered doping. Many professional athletes have been disqualified because of their use. This fact proves the effectiveness of MK-677. Traces of the drug are kept for up to 3-4 months in the blood. Do not exceed the recommended dosage!
Best place to buy MK-677 online? Recommended SARMs Vendors
Check the trusted brands to order SARMs online. Read the best SARM companies here.
Mike Lilley is the author of many articles and reviews on our site. He is a fitness & bodybuilding blogger and co-founder of Boost Hormone. He writes product reviews based on the results of scientific research. From the great variety of information and products in this niche, he recommends only those that include science-based nutritional ingredients. Find Mike Lilley at SelfGrowth.
- Ralf Nass, Suzan S Pezzoli, Mary Clancy Oliveri…
“Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized Trial” – Ann Intern Med. 2008 Nov 4;149(9):601-11. https://pubmed.ncbi.nlm.nih.gov/18981485/
I M Chapman, O H Pescovitz, G Murphy, T Treep, K A Cerchio, D Krupa, B Gertz, W J Polvino, E H Skiles, S S Pezzoli, M O Thorner
“Oral Administration of Growth Hormone (GH) Releasing Peptide-Mimetic MK-677 Stimulates the GH/insulin-like Growth factor-I Axis in Selected GH-deficient Adults ” –
J Clin Endocrinol Metab. 1997 Oct;82(10):3455-63. doi: 10.1210/jcem.82.10.4297. https://pubmed.ncbi.nlm.nih.gov/9329386/
J. Svensson, L. Lönn, J.-O. Jansson, G. Murphy, D. Wyss, D. Krupa, K. Cerchio, W. Polvino…
“Two-Month Treatment of Obese Subjects with the Oral Growth Hormone (GH) Secretagogue MK-677 Increases GH Secretion, Fat-Free Mass, and Energy Expenditure” –
The Journal of Clinical Endocrinology & Metabolism, Volume 83, Issue 2, 1 February 1998, Pages 362–369 https://academic.oup.com/jcem/article/83/2/362/2865156
“An Anti-frailty Pill For Seniors? New Drug Increases Muscle Mass In Arms And Legs Of Older Adults” –
University of Virginia Health System November 5, 2008 https://www.sciencedaily.com/releases/2008/11/081104132902.htm
G Copinschi, A Van Onderbergen, M L’Hermite-Balériaux, C M Mendel, A Caufriez, R Leproult, J A Bolognese, M De Smet, M O Thorner, E Van Cauter”Effects of a 7-day Treatment With a Novel, Orally Active, Growth Hormone (GH) Secretagogue, MK-677, on 24-hour GH Profiles, Insulin-Like Growth Factor I, and Adrenocortical Function in Normal Young Men ” –
J Clin Endocrinol Metab. 1996 Aug;81(8):2776-82. https://pubmed.ncbi.nlm.nih.gov/8768828/