The best SARMs for cutting are MK-677, Andarine (S4), or Stenabolic (SR9009)? How to stack them to benefit and get the best and fast results in bodybuilding?
The stacks reviewed today are used to prepare for the competition (for cutting). The solo SARM cycle is ok, but you will get faster and better results stacking two selective androgen receptor modulators.
Two combinations of the three SARMs reviewed below accelerate lipolytic processes. The release of triglycerides from the adipose tissue is accelerated with the subsequent burning of free fatty acids in the mitochondria of muscle cells. The activation of energy metabolism helps to gain lean muscle mass. Another effect is strengthening ligaments, tendons, and joints, increasing the strength of the musculoskeletal system.
Let’s get down to the first combination of two of the best SARM stacks for cutting.
MK-677 (Ibutamoren, Nutrobal) + Andarine (S4)
Is it possible to gain lean muscles without anabolic steroids? The cutting cycle solves this problem: your steroid-free training will finally begin to yield the long-awaited results, and you will start seeing more detailed muscles soon!
Stacked SARM cycles have a massive advantage over any solo cycle. Using two drugs, you activate anabolic and lipolytic processes in two directions at once. The critical condition for maximum effectiveness of the stack cycle is the correct selection of drugs – the fat-burning and muscle-building must not compete and complement each other, having a synergistic effect.
The best SARMs for cutting are meeting this condition. The stack activates different links of the anabolic chain.
Andarine’s selectivity is manifested because it activates testosterone receptors only in connective tissues – fat, muscle, cartilage, and bone.
S4 doesn’t affect the pituitary, hypothalamus, and glands! Thanks to this feature, these SARMs for cutting show the maximum anabolic-lipolytic potential without adverse side effects.
According to a [Gao et al., Endocrinology, 2005] study published in Endocrinology, Andarine (S4) demonstrated potent anabolic activity in skeletal muscle and bone while showing “weak androgenic activity in the prostate,” effectively restoring muscle mass and strength in hypogonadal models without the significant prostate enlargement seen with traditional androgens.
MK-677 belongs to the agonists of ghrelin receptors. These are special receptors in the hypothalamus and pituitary gland. The activation of the receptors enhances the secretion of Growth Hormone.
There is no need to talk about the role of HGH in fitness and bodybuilding. Along with testosterone, somatotropin is the primary lipolytic and anabolic hormone. We should not forget that another feature of GH – it accelerates the restoration of connective tissues, strengthening the tendons, joints, and ligaments.
This SARMs cutting stack is a double activation of metabolic shifts, causing a powerful anabolic-lipolytic explosion! Two products do not compete and only multiply the final result.
Andarine + MK-677 cycle for fat loss
Both SARMs accelerate lipolytic (fat burning) processes.
According to a [Nass et al., Annals of Internal Medicine, 2008] randomized double-blind study, MK-677 treatment increased growth hormone and IGF-1 levels to those of healthy young adults and prevented the decline in fat-free mass, with results showing that “MK-677 significantly increased fat-free mass by 1.1 kg” while simultaneously decreasing abdominal visceral fat.
Due to the activation of androgenic receptors and increased production of GH, the burning of triglycerides of fatty tissue increases. Fatty acids entering the blood are burned in muscle cells and provide energy for training, regeneration, and muscle growth.
Thanks to the activation of an energy boost on a cycle, it is possible to lose weight or decrease fat and lean muscle gains.
Muscle building without steroids is not so rapid, but it has its advantage – after stopping the cycle, there will be no immediate loss of the gained muscle, as in the case with steroids. Safe non-steroidal cycle Andarin + Ibutamoren will provide stable muscle growth, and the result will remain forever.
Main Benefits and Effects of Andarine + MK-677 Stack:
- Lipolytic: accelerates the burning of fats.
- Cutting: increases the depth and detail of the muscles, enhances vascularity.
- Anti-Catabolic: prevents the breakdown of proteins, which is especially important during periods of cutting and slimming.
- Anabolic: stimulates muscle hypertrophy and, with the proper diet, guarantees to increase lean muscle mass and keep it.
The impact of the Andarine + MK-677 cycle on health:
Increases the mineralization (density) of bone tissue;
Increasing the strength of joints, tendons, and ligaments;
It reduces the risk of chronic diseases of the musculoskeletal system (arthritis, arthrosis) and minimizes the threat of sports injuries.
Another advantage of MK-677 + S4 stack for cutting – the unique combination of high efficiency and excellent safety profile! Do NOT inhibit the production of your sex hormones, do NOT cause gynecomastia, hair loss, and other problems characteristic to anabolics. The stunning steroid-free muscle mass is accurate.
How do I take Andarin + Ibutamoren stack?
For cutting: Andarin 2 capsules a day, take 2 times a day. Ibutamoren 1-2 capsules a day, take 1-2 times a day. The duration of the cycle is 8 weeks.
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Stenabolic + Andarine SARMs for Cutting
The combination of Stenabolic and Andarine is genuinely unique, and it’s the second of the best SARMs for cutting stacks reviewed in the article. Both SARMs show high lipolytic activity. They normalize carbohydrate metabolism, accelerate fat breakdown, increase energy consumption when working out and at rest.
The stack improves the blood lipid profile, lowers the concentration of bad cholesterol, and lowers plasma markers, which signal a high risk of serious chronic diseases.
Stenabolic + Andarine is the ideal combination for preparing for competition. The synergistic effect of drugs on energy, carbohydrate, and fat metabolism is shown by the following metabolic changes:
- Increasing the level of basal metabolism.
- Increase in calorie consumption at rest and when working out.
- The decrease in the synthesis of triglycerides.
- Improvement of glucose metabolism.
- Accelerated utilization of free fatty acids in oxidative reactions.
According to a [Solt et al., Nature, 2012] study on the REV-ERB agonist SR9009, administration of the compound to mice increased metabolic rate and endurance while decreasing fat mass, observing that “SR9009 treated mice exhibited a 12% decrease in plasma triglycerides and a 47% decrease in plasma total cholesterol.” The study confirmed that activation of REV-ERB significantly alters circadian metabolism to favor energy expenditure and lipid oxidation.
These changes enhance the body’s fat-burning potential and increase the productivity of power and cardio training. Andarine’s anti-catabolic action is significant. We should not forget that the priority task while cutting is to preserve muscle mass. Andarine is explicitly designed for the treatment of muscle atrophy, perfectly copes with the suppression of destructive catabolism.
Positive changes in energy metabolism affect the visual component and the functional training of the athlete. Stenabolic + Andarine increases anaerobic (strength) and aerobic (cardio) endurance.
Another important thing is the reduction of muscle and joint pains. Stenabolic 72% reduces the concentration of pro-inflammatory cytokines – biologically active substances responsible for developing inflammatory reactions.
The effects of the non-steroidal cycle Stenabolic + Andarine:
- Improvement of body composition: a decrease in fat percentage, the growth of lean mass.
- Increasing the density of skeletal muscles.
- Strengthening the venous pattern.
- Boost of strength and speed.
- Increase in power and aerobic endurance.
- Acceleration of recovery.
- Reducing muscle and joint pains.
Safety Profile
Stenabolic and Andarine do not harmfully affect the production of their hormones, do not inhibit the synthesis of FSH, LH, endogenous testosterone. SARMs are not affected by the enzymes 5-alpha-reductase. There are no side effects caused by an increase in DHT or estrogen levels during the administration. Aromatase inhibitors or estrogen receptor blockers do not need to be taken.
According to a [Wen et al., Clinical Endocrinology, 2025] systematic review of SARM safety, while SARMs generally spare the prostate compared to anabolic steroids, they are not devoid of side effects, with data showing “statistically significant suppression of HDL cholesterol and triglycerides” across multiple trials. Users should monitor lipid profiles, as the majority of patients were able to recover baseline values after cessation, but temporary suppression of natural testosterone and lipids is a documented risk.
How to take Stenabolic + Andarine SARMs for cutting?
The recommended dosage of Stenabolic: 24-36 mg/day; it should be divided into 2-3 doses of 12 mg each.
The recommended dosage of Andarine: 25-50 mg/day; it should be divided into 1-2 intakes of 25 mg.
Cycle duration: 8 weeks.
Where to buy the best quality SARMs with discounts?
We advise you to order SARMs online only from the trusted brands (we share discount coupons) – best SARM companies review here.
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References:
- Endocrinology (2005) – “Selective Androgen Receptor Modulator Treatment Improves Muscle Strength and Body Composition and Prevents Bone Loss in Orchidectomized Rats”
Confirming Andarine (S4) restores soleus muscle mass and strength and cortical bone mass in castrated rats without significant prostate stimulation. “S-4 demonstrated potent anabolic activity in increasing skeletal muscle mass and strength and in maintaining bone mass.”
https://pmc.ncbi.nlm.nih.gov/articles/PMC2039881/ - Annals of Internal Medicine (2008) – “Effects of an Oral Ghrelin Mimetic on Body Composition and Clinical Outcomes in Healthy Older Adults”
Clinical trial showing MK-677 increases GH and IGF-1 to young-adult levels. “MK-677 significantly increased fat-free mass…and decreased abdominal visceral fat,” supporting its use for body recomposition.
https://www.acpjournals.org/doi/10.7326/0003-4819-149-9-200811040-00003 - Nature (2012) – “Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists” Pivotal study on SR9009 demonstrating its effect on metabolic rate. “SR9009 treated mice exhibited a more severe reduction in adiposity…a 12% decrease in plasma triglycerides and a 47% decrease in plasma total cholesterol.”
https://pmc.ncbi.nlm.nih.gov/articles/PMC3343186/
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