Best HGH Spray: My Top Natural Growth Hormone Supplements List

The best HGH sprays are easy-to-use supplements designed to boost your body’s natural growth hormone levels, helping with energy, muscle strength, and recovery. Top picks focus on safe ingredients, proven results, and positive user reviews—but not all sprays deliver as promised. In this guide, we’ll break down what makes an HGH spray effective and how to choose one that fits your health goals.

Among the top contenders, Sytropin HGH Spray stands out with its blend of ingredients like OAG, L-arginine, and Moomiyo Extract, offering benefits such as lean muscle growth and anti-aging effects, priced between $59.95 and $199.95 with a 90-day money-back guarantee.

Another notable option, HGH 30 000 Nanograms, combines amino acids, growth factors, and homeopathic HGH with Deer Antler Velvet, recommended for use before bedtime. Genf20 Plus, with key components like Alpha GPC and L-Arginine, focuses on increasing strength and improving mental function, with a usage protocol of six sprays daily.

These sprays advocate a natural approach to anti-aging and health, working to boost HGH production sublingually, a method preferred for its convenience and effectiveness. The health benefits of HGH sprays, such as faster muscle recovery and enhanced lipolysis, align with a holistic wellness philosophy.

Moreover, these supplements are legal, do not require a prescription, and are designed for easy on-the-go application, making them a practical solution for individuals aiming to increase their growth hormone levels naturally.

Review of the Best Homeopathic HGH Sprays

✔️ Sytropin HGH Spray

You may have heard about Sytropin as a good booster for muscle growth without using anabolic steroids. Sytropin is an HGH supplement that has been used for years by professional athletes and, more recently, is becoming popular amongst the general public looking for an effective method for faster lean muscle growth and repair.

Sytropin has also become popular to help combat the signs of aging. Some experts even believe that growth hormone can be the key to slowing down or even stopping the age-related deterioration of the body, although there are currently no peer-reviewed medical studies to back up this hypothesis

The natural ingredients included in Sytropin HGH spray are:

• OAG (Ornithine Alpha-Ketoglutarate) –
  

  According to [Soul Performance Nutrition, 2022], “OAG is built from L-ornithine and alpha-ketoglutarate (AKG), with L-ornithine serving as a nitrogen shuttle in protein synthesis while AKG participates in the Krebs cycle for ATP energy production. Together, OAG enhances nitric oxide (NO) biosynthesis, promoting vasodilation that increases oxygen and nutrient delivery to muscle tissues, supporting greater endurance, faster recovery, and a muscle environment primed for growth.”

• L-arginine amino-acid,
• An extract of L-Dopa bean,
• The L-Glutamine amino-acid accelerates the metabolism of the body,
• Moomiyo Extract – rebuilds your collagen,
• Gamma-aminobutyric acid, or GABA, for better sleep, nervous system functioning, and improved growth hormone release while you are sleeping,
  

  According to [Walzer et al., PMC, 2021], “Single-dose GABA receptor modulation (ASP8062 at 35 and 70 mg) resulted in CNS penetration with enhanced GABAergic activity as measured by statistically significant increases in slow-wave sleep and growth hormone release. The increase in slow-wave sleep and GH primarily occurred during the first third of the night, when pulsatile GH release and sleep pressure are greatest.”

• Alpha GPC,
  

  According to [Kerksick et al., Lindenwood University, 2025], “A randomized double-blind placebo-controlled trial showed that Alpha-Glycerylphosphorylcholine (A-GPC) supplementation at both 630 mg and 315 mg doses significantly improved Stroop test cognitive performance scores compared to placebo. The study also found that A-GPC is linked to growth hormone secretion in athletes and prevents exercise-induced choline depletion, enhancing both cognitive and physical performance.”

• L-dihydroxyphenylalanine (L-DOPA)

The potential benefits of an HGH releaser like Sytropin, include:

• growth of lean muscle mass and increased bone density.
  

  According to [Hammarqvist et al., PMC, 1992], “Synthetic HGH administered post-operatively impeded the significant postoperative decrease in total ribosome concentration (15.3±6.4%) and polyribosome concentration (20.9±6.5%) seen in control groups. The hGH group showed preserved levels of muscle free glutamine and improved whole-body nitrogen balance, indicating maintained capacity for protein synthesis in skeletal muscle.”

• burn fat (this is likely due to the increased muscles rather than Sytropin itself).
  

  According to [HGH Lipolysis Research, Karger, 2003], “The 20-kD human growth hormone variant significantly reduced body fat through dose-dependent inhibition of lipoprotein lipase activity in adipose tissue and stimulation of lipolysis in adipocytes. Growth hormone produces substantial increases in free fatty acids within 1–2 hours, typically doubling baseline levels, reflecting enhanced mobilization of fat stores for energy.”

• probably lessening some signs of aging.
• reduce your stress levels.

For best effect, HGH must be taken by injection or as a sublingual spray (natural GH booster) to bypass the digestive tract and go straight to the bloodstream.

According to [Sublingual Drug Delivery Review, JDDT, 2025], “Sublingual administration avoids first-pass metabolism in the liver and gastric acid hydrolysis of drugs, thereby showing increased oral bioavailability. The sublingual epithelium thickness of 100-200 micrometers is much less than buccal thickness, allowing absorption to be faster. Due to high permeability and rich blood supply, the sublingual route produces rapid onset of action, with the drug absorbed through sublingual blood vessels bypassing the hepatic portal system.”

Where to buy Sytropin HGH spray

You can obtain the one-month supply pack for $59.95 by buying the item at the official site. When you buy two or more bottles, there are some excellent discount rates. You can select the 3-month pack for just $119.95 and save a lot. The best pack includes a 6-month supply and is only $199.95.

The business uses the very best money-back warranty. You can return the item and also obtain a total reimbursement of your cash within 90 days if you are not pleased with the product.

Learn More About Sytropin

✔️ HGH 30 000 Nanograms

The HGH 30000 Nanos spray is one of the highest-rated sprays, both by user testimonials and online reviews. The first is its formulation and the high dosage of natural ingredients used to produce the HGH 30000 spray, which ensures it effectively boosts the production of HGH.

One of the benefits of this sublingual HGH is that you will not have to wait for months to see its results. The very first results, like better sleep and enhanced energy levels, are almost immediately seen.

The HGH supplement uses various ingredients which include, in total, eight different amino acids (HGH releasers) , 6 growth factor, and homeopathic HGH. All these ingredients will help you to feel better, look better, and enhance your overall physical performance.

The Soma HGH also includes Deer Antler Velvet, which provides you with the required anabolic effect.

According to [Marmillo et al., UNLV Dissertation, 2018], “Deer antler velvet contains high concentrations of IGF-1, IGF-2, amino acids, and over 390 micro and macro elements. Clinical studies show that deer antler velvet supplementation significantly improved 1-RM strength values in absolute and relative terms to total body weight, with improvements in aerobic capacity of 9.8% (p=.002) and isokinetic knee extensor strength increases of 30±21% versus 13±15% in placebo groups (p=.04).”

There are no known reported side effects of this HGH supplement. It is very easy to use, just take 2-3 sprays before hitting the bed.

It also comes with a 90-day money-back guarantee. The only disadvantage is that this is one of the most expensive HGH supplements available on the market. When you look at the quality of the best ingredients used and the formulation, you will think that it can worth the price.

✔️ Genf20 Plus

As already mentioned earlier, the pituitary gland present in your body must generate the desired levels of HGH in your body. And as you age, this functionality of the pituitary gland also diminishes, and to maintain the production of HGH at a certain level, you have to take the help of outside supplements.

The Genf20 Plus designed by Leading Edge Health is one such supplement that reminds your pituitary gland to function properly, or you can say that it stimulates the pituitary gland to produce and release HGH as if you are still in your 20s.

One of the main natural ingredients of Genf20 Plus is Alpha GPC. This component is capable of increasing the secretion of HGH, removing fat from the liver, enhancing mental function and improving heart health. L-Tyrosine (a neurotransmitter that stimulates the brain to release growth hormone), L-Lysine, L-Arginine, GABA, Mucuna Pruriens, Colostrum, and other key ingredients are also included.

The very effective and efficient combination of natural ingredients present in the Genf20 Plus is capable of providing users with various benefits, such as increased strength and workout endurance, increased fat elimination from your liver, better mental function, and prevention of diabetes and obesity.

It is very convenient to use, and you only need about six sprays of Genf20 Plus throughout the day. You can purchase it separately or in combination with the Genf20 Plus supplement. Both of these products are completely safe, and there are no known side effects to them.

The Genf20 Plus comes with a 60-day money-back guarantee. The only disadvantage of Genf20 Plus is that its ingredient list is not as rich as the ones used in HGH 30000 Nano Sprays, hence, it is recommended to take it with Genf20 Plus Supplement to get the maximum possible results.

Learn More About Genf20 Plus Benefits

Do HGH sprays work well?

Let’s take the spray’s philosophy. The sublingual spray releaser does not include a hormonal agent, however, it sets off and also boosts your body to enhance the secretion of growth hormones. Since it is your very own body that is launching these useful nutrients into your system, this method is currently an all-natural anti-aging one.

Instead of infusing pure GH right into your body, the Sytropin or GenF20 Plus are taken orally. The mix of the tablets and sublingual and oral spray interact and work simultaneously to reach your body most successfully and start HGH production the natural way.

Overall Health benefits of using HGH sprays

Muscle recovery and beyond: proponents of HGH sprays highlight their potential to:

• Boost muscle recovery: HGH is known to stimulate protein synthesis, potentially aiding in repairing muscle tissue after workouts and leading to faster recovery times.
• Enhance fat burning: HGH may promote lipolysis, the breakdown of fat stores, potentially contributing to weight management and a leaner physique.
• Improve energy levels: Increased HGH levels could lead to enhanced stamina and vitality, combating fatigue and boosting overall energy.
• Strengthen hair and nails: HGH plays a role in cell growth and regeneration, potentially contributing to healthier hair and nails.
• Improve cognitive function: Some studies suggest HGH may have a positive impact on memory and cognitive performance, although further research is needed.

While these possibilities sound promising, the science surrounding HGH sprays is still evolving.

FAQ

✔️ What is HGH Spray?

It’s an HGH releaser, which you will take orally by spraying it into your mouth. It is fast and easy to administer. It will always be great to have it with you when on the move. Also, for those suffering from Dysphagia (the fear of or inability to take tablets or capsules). The ingredients will bypass the digestive system and the liver and go right into the bloodstream.

✔️ How to Use HGH Sprays?

Although usage instructions are always provided with the package, generally it is advised to use just 2 sprays, under the tongue, 3 times per day.

It works wonderfully if you use it right before you go to sleep and immediately after you wake up. The third dose can be taken at any time during the day. After a few months, you can also skip this third dose entirely and just keep going with two dozes: one in the morning and once at night.

✔️ How can I increase HGH naturally?

This may seem a bit boring, but only a full night’s sleep, a healthy diet, some supplements, and regular exercise can stimulate the production of growth hormone naturally. Those who want to maintain their youth and beauty and increase muscle tone for as long as possible should take rest and a balanced diet more seriously with each decade.

• The most powerful natural HGH releaser is prolonged sleep: about 85% of the hormone is secreted when we sleep. The highest peak is at night, one or two hours after falling asleep. That’s why it’s recommended to take HGH releasers and some amino acids in free form just before going to bed.

• Any physical activity – a short run, a walk in the fresh air – already stimulates the production of somatotropin.

• Good nutrition also contributes to this. It is important to avoid fatty foods and foods with a high glycemic index, as well as to ensure that your diet has sufficient protein and amino acids. Improper nutrition not only does not contribute to the production of growth hormone but also significantly reduces its secretion. Therefore, without a healthy diet, HGH production is reduced. Refined sugar also helps to slow down the production of growth hormone, as does a diet that is not balanced in terms of vitamins and trace elements.

In addition, you can stimulate the production of growth hormones by including pineapples, coconut milk, raspberries, pumpkin seeds, soybeans, fish, peanuts, chicken, and spirulina in your daily diet, and after training, you can drink a protein-carbohydrate shake.

✔️ Is HGH illegal?

Buying and using injectable HGH without a prescription is not legal in the USA. You can only get it from a doctor by prescription. All the other stuff written above is legal.

✔️ Customer Reviews of the Top Sprays

What do you think about these products? If you have any experience (positive or negative) with using one of these HGH sprays, feel free to write a short review below! Just put the product name you are reviewing into the “Review Title” field.

References

1. [Soul Performance Nutrition, 2022] – “OKG: The Unsung Hero of Athletic Performance and Muscle Health” Explains that OAG (Ornithine Alpha-Ketoglutarate) is composed of L-ornithine and alpha-ketoglutarate, where L-ornithine functions as a nitrogen shuttle for protein synthesis while AKG participates in the Krebs cycle for ATP energy production. The combination enhances nitric oxide biosynthesis, promoting vasodilation that increases oxygen and nutrient delivery to muscle tissues.
2. [Walzer et al., PMC, 2021] – “A randomized phase 1 single-dose polysomnography study of ASP8062 (a GABA-B receptor positive allosteric modulator)” A clinical polysomnography study showing that GABA-B receptor modulation resulted in enhanced GABAergic activity with statistically significant increases in slow-wave sleep and growth hormone release. The study demonstrated that increased slow-wave sleep and GH primarily occurred during the first third of the night, when pulsatile GH release and sleep pressure are greatest.
3. [Kerksick et al., Lindenwood University, 2025] – “Acute Alpha-GPC supplementation provides cognitive boost in healthy men” A randomized double-blind placebo-controlled crossover trial in resistance-trained males showing that Alpha-Glycerylphosphorylcholine (A-GPC) supplementation at 630 mg and 315 mg doses significantly improved Stroop test cognitive performance scores. The study also documented that A-GPC is linked to growth hormone secretion and prevents exercise-induced choline depletion.
4. [Hammarqvist et al., PMC, 1992] – “Biosynthetic human growth hormone preserves both muscle protein synthesis and whole-body nitrogen economy” A clinical study showing that synthetic HGH administration impeded the significant postoperative decrease in total ribosome concentration (15.3±6.4%) and polyribosome concentration (20.9±6.5%) observed in control groups. The HGH group showed preserved levels of muscle free glutamine and significantly improved whole-body nitrogen balance, indicating maintained capacity for protein synthesis.
5. [HGH Lipolysis Research, Karger, 2003] – “The 20-kD Human Growth Hormone Reduces Body Fat by Inhibiting LPL Activity and Stimulating Lipolysis” Research demonstrating that the 20-kD HGH variant significantly reduced body fat through dose-dependent inhibition of lipoprotein lipase (LPL) activity in adipose tissue and stimulation of lipolysis in adipocytes. Growth hormone produces substantial increases in free fatty acids within 1–2 hours, typically doubling baseline levels, reflecting enhanced mobilization of fat stores for energy.
6. [Sublingual Drug Delivery Review, JDDT, 2025] – “Sublingual route for systemic drug delivery” A comprehensive review of sublingual drug delivery explaining that this route avoids first-pass metabolism in the liver and gastric acid hydrolysis of drugs, thereby showing increased oral bioavailability. The sublingual epithelium thickness of 100-200 micrometers is much thinner than buccal thickness, allowing absorption to be faster, and due to high permeability and rich blood supply, the sublingual route produces rapid onset of action.
7. [Marmillo et al., UNLV Dissertation, 2018] – “Changes in IGF-1 Levels Post Deer Antler Velvet Supplementation” A comprehensive dissertation documenting that deer antler velvet contains high concentrations of IGF-1, IGF-2, amino acids, and over 390 micro and macro elements. Clinical studies show that deer antler velvet supplementation significantly improved 1-RM strength values in absolute and relative terms to total body weight, with improvements in aerobic capacity of 9.8% and isokinetic knee extensor strength increases of 30±21% versus 13±15% in placebo groups.

Research Team

The BoostHormone Research Team is a collective of fitness researchers, nutrition specialists, and health science professionals dedicated to providing evidence-based information about hormone optimization and performance enhancement.

With expertise in sports nutrition, endocrinology, and supplement science, our team analyzes peer-reviewed research and clinical studies to deliver honest, science-backed insights. We cut through industry hype to provide the accurate information you need to make informed decisions about your health and performance.

Our mission: translate complex scientific research into practical, actionable guidance – always prioritizing your safety and long-term wellness. Read Our Editorial Guidelines.

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